The incidence of age-related diseases such as cancer and osteoporosis is rapidly increasing, and extending healthy life expectancy together with improving quality of life (QOL) has become an urgent social priority. Our laboratory focuses on brain diseases, one of the major medical challenges of the 21st century, and is dedicated to the creation of novel small-molecule compounds through chemical synthesis. In particular, we are exploring candidate compounds for the treatment of neurodegenerative disorders, including Alzheimer’s disease, with the goal of establishing innovative therapeutic strategies that enable neural regeneration. If successful, this research has the potential to regenerate lost neurons and slow or even halt disease progression. Our research themes include: The design and synthesis of small molecules that induce the differentiation of neural stem cells into neurons, The discovery of compounds that suppress the replication of SARS-CoV-2, The design and synthesis of novel compounds targeting nuclear receptors, and The synthesis of chemical probes that contribute to a deeper understanding of fundamental life phenomena.